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9 p, 748.2 KB |
Unmet Needs in the Management of Moderate-to-Severe Psoriasis in Spain : A Multidimensional Evaluation
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Zozaya, Néboa (Universidad de Las Palmas de Gran Canaria) ;
Villoro, Renata (Weber Foundation) ;
Abdalla, Fernando (Weber Economía y Salud) ;
Alfonso Zamora, Santiago (Psoriasis and Psoriatic Arthritis Patient and Family Association) ;
Balea Filgueiras, Jesús (Complejo Hospitalario Universitario de Ferrol) ;
Carrascosa, José Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Delgado Sánchez, Olga (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Dolz Sinisterra, Francisco (Hospital Universitari Doctor Peset (València)) ;
García-Ruiz, Antonio (Instituto de Investigación Biomédica de Málaga) ;
Herranz Pinto, Pedro (Hospital Universitario La Paz (Madrid)) ;
Manfredi, Antonio (Psoriasis and Psoriatic Arthritis Patient and Family Association) ;
Martínez Olmos, José (Escuela Andaluza de Salud Pública) ;
Morales de los Ríos, Paloma (Hospital General Universitario Gregorio Marañón) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Ros Abarca, Sandra (Institut d'Investigació Biomèdica Sant Pau) ;
Hidalgo, Álvaro (Universidad de Castilla-La Mancha) ;
Universitat Autònoma de Barcelona
Psoriasis is a chronic, systemic inflammatory disease that affects the skin, with a high impact on patients' quality of life. The aim of this study was to identify and determine the relative importance of unmet needs in the management of moderate-to-severe psoriasis in Spain, from a multi-stakeholder perspective. [...]
2022 -  10.2340/actadv.v102.583
Acta dermato-venereologica, Vol. 102 (2022) , p. adv00678
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5 p, 414.7 KB |
Long-term impact of ixekizumab on psoriasis itch severity : Results from a phase III clinical trial and long-term extension
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Kimball, Alexandra B. (Beth Israel Deaconess Hospital and Harvard Medical School) ;
Luger, Thomas (University of Muenster) ;
Gottlieb, Alice (New York Medical College) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Kaufmann, Roland (Goethe University) ;
Burge, Russel (University of Cincinnati) ;
Lin, Chen-Yen (Eli Lilly and Company) ;
Yosipovitch, Gil (University of Miami Miller School Of Medicine) ;
Universitat Autònoma de Barcelona
Itching is a prevalent plaque psoriasis symptom. Ixekizumab, an IL-17A antagonist, has demonstrated rapid, significant improvements in itch severity over 12 weeks in Phase III psoriasis trials (UNCOVER-1, UNCOVER-2). [...]
2018 - 10.2340/00015555-2801
Acta dermato-venereologica, Vol. 98 Núm. 1 (2018) , p. 98-102
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7 p, 1.3 MB |
Absolute and relative psoriasis area and severity indices (PASI) for comparison of the efficacy of ixekizumab to etanercept and placebo in patients with moderate-to-severe plaque psoriasis : An integrated analysis of UNCOVER-2 and UNCOVER-3 outcomes
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Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Dossenbach, Martin (Eli Lilly and Company) ;
Berggren, Lovisa (Lilly Deutschland GmbH) ;
Ljungberg, Anders (Eli Lilly and Company) ;
Zachariae, Claus (University of Copenhagen) ;
Universitat Autònoma de Barcelona
Treatment goals defined by the absolute Psoriasis Area and Severity Index (PASI) scores offer certain advantages in the clinical setting. In order to investigate potential treatment targets, this study evaluated absolute PASI outcomes relative to other measures of response using data from two randomized clinical trials of patients with moderate-to-severe psoriasis treated with ixekizumab, etanercept, or placebo (n=2,567). [...]
2019 - 10.2340/00015555-3245
Acta dermato-venereologica, Vol. 99 Núm. 11 (october 2019) , p. 971-977
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7 p, 769.8 KB |
An analysis of patient-reported outcomes in ixora-s : Comparing ixekizumab and ustekinumab over 52 weeks in moderate-to-severe psoriasis
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Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Lomaga, Mark (DermEdge Research and Probity Medical Research) ;
Hollister, Kristin (Eli Lilly and Company) ;
Dutronc, Yves (Eli Lilly and Company) ;
Berggren, Lovisa (HaaPACS GmbH) ;
Van De Kerkhof, Peter C.M. (Radboud University Nijmegen Medical Centre) ;
Universitat Autònoma de Barcelona
Patient-reported outcomes are valuable for assessing new psoriasis therapies. This study investigated patient-reported outcomes in patients with moderate-to-severe plaque psoriasis treated with ixekizumab or ustekinumab, dosed according to their respective labels, for 52 weeks (IXORA-S-NCT02561806). [...]
2020 - 10.2340/00015555-3700
Acta dermato-venereologica, Vol. 100 Núm. 19 (2020) , p. 1-7
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8 p, 509.9 KB |
Psoriasis and mental health workshop report : Exploring the links between psychosocial factors, psoriasis, neuroinflammation and cardiovascular disease risk
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Kleyn, C.Elise (Manchester Academic Health Science Centre) ;
Talbot, Peter S. (University of Manchester) ;
Mehta, Nehal N. (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ;
Sampogna, Francesca (IDI-IRCCS) ;
Bundy, Chris (Cardiff University) ;
Ashcroft, Darren M. (University of Manchester) ;
Kimball, Alexa B. (Beth Israel Deaconess Medical Center) ;
van de Kerkhof, Peter C.M. (International Psoriasis Council) ;
Griffiths, Christopher E.M. (NIHR Manchester Biomedical Research Centre) ;
Valenzuela, Fernando (University of Chile and Probity Medical Research) ;
van der Walt, Joelle M. (International Psoriasis Council) ;
Aberra, Tsion (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ;
Puig-Verdié, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Psoriasis is a systemic, relapsing, inflammatory disease associated with serious comorbidities including mood problems and/or unhealthy lifestyle behaviours. Cutaneous and systemic abnormalities in innate and acquired immunity play a role in its pathogenesis. [...]
2020 - 10.2340/00015555-3375
Acta dermato-venereologica, Vol. 100 Núm. 1 (january 2020) , p. adv00020
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8 p, 492.9 KB |
Cardiovascular Screening Practices and Statin Prescription Habits in Patients with Psoriasis among Dermatologists, Rheumatologists and Primary Care Physicians
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Berna-Rico, Emilio (Hospital Universitario Ramón y Cajal (Madrid)) ;
Abbad-Jaime de Aragon, Carlota (Hospital Universitario Ramón y Cajal (Madrid)) ;
Garcia-Aparicio, Ángel (Hospital Universitario de Toledo) ;
Palacios-Martinez, David (Centro de Salud Universitario Isabel II) ;
Ballester-Martínez, Asunción (Hospital Universitario Ramón y Cajal (Madrid)) ;
Carrascosa, José Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
De la Cueva, Pablo (Hospital Universitario Infanta Leonor) ;
Anton, Cristina (Universidad Francisco de Vitoria, Madrid) ;
Azcarraga-Llobet, Carlos (Hospital Universitario Ramón y Cajal (Madrid)) ;
Garcia-Mouronte, Emilio (Hospital Universitario Ramón y Cajal (Madrid)) ;
De Nicolas-Ruanes, Belén (Hospital Universitario Ramón y Cajal (Madrid)) ;
Puig-Verdié, Lluís (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Jaen, Pedro (Hospital Universitario Ramón y Cajal (Madrid)) ;
Mehta, Nehal N. (National Institutes of Health (Estats Units)) ;
Gelfand, Joel M. (University of Pennsylvania Perelman School of Medicine (Estats Units)) ;
Gonzalez-Cantero, Álvaro (Universidad Francisco de Vitoria (Madrid)) ;
Universitat Autònoma de Barcelona
Patients with psoriasis have a higher prevalence of cardiovascular risk factors. This study evaluated cardio-vascular screening practices and statin prescribing habits among dermatologists, rheumatologists and primary care physicians (PCPs) through an online questionnaire, which was distributed through the Spanish scientific societies of the above-mentioned specialties. [...]
2023 - 10.2340/actadv.v103.5087
Acta dermato-venereologica, Vol. 103 (march 2023)
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7 p, 720.5 KB |
Chronic nodular prurigo : A european cross-sectional study of patient perspectives on therapeutic goals and satisfaction
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Pereira, Manuel Pedro (University Hospital of Münster (Alemanya)) ;
Zeidler, Claudia (University Hospital of Münster (Alemanya)) ;
Wallengren, Joanna (Department of Clinical Sciences Lund. Dermatology and Venereology. Lund University. Lund Sweden. Skåne University Hospital) ;
Halvorsen, Jon Anders (Oslo University Hospital (Oslo, Noruega)) ;
Weisshaar, Elke (Department of Social Medicine. Occupational and Environmental Dermatology. University of Heidelberg) ;
Garcovich, Simone (Università Cattolica del Sacro Cuore) ;
Misery, Laurent (University Hospital of Brest) ;
Brenaut, Emilie (Department of Dermatology. University Hospital of Brest) ;
Savk, Ekin (Department of Dermatology. Aydın Adnan Menderes University) ;
Potekaev, Nikolay (Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology) ;
Lvov, Andrey (Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology) ;
Bobko, Svetlana (Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology) ;
Szepietowski, Jacek C. (Wroclaw Medical University. Department of Dermatology. Venereology and Allergology) ;
Reich, Adam (University of Rzeszów. Department of Dermatology) ;
Bożek, Agnieszka (University of Information Technology and Management. School of Medicine) ;
Legat, Franz Josef (Medical University of Graz. Department of Dermatology) ;
Metz, Martin (Charité - Universitätsmedizin Berlin) ;
Streit, Markus (Department of Dermatology. Kantonsspital Aarau) ;
Serra-Baldrich, E (Institut d'Investigació Biomèdica Sant Pau) ;
Gonçalo, Margarida (University of Coimbra. Department of Dermatology) ;
Storck, Michael (University of Münster. Institute of Medical Informatics) ;
Nau, Teresa (University Hospital of Münster (Alemanya)) ;
Hoffmann, Vincent (University Hospital of Münster (Alemanya)) ;
Steinke, Sabine (University Hospital of Münster (Alemanya)) ;
Greiwe, Ina (University Hospital of Münster (Alemanya)) ;
Dugas, Martin (Institute of Medical Informatics. University of Münster) ;
Augustin, Matthias (University Medical Center Hamburg-Eppendorf) ;
Ständer, Sonja (University Hospital Muenster (Alemanya))
Chronic nodular prurigo is characterized by recalcitrant itch. Patient perspectives on therapeutic goals, satisfaction with therapy and efficacy of therapeutic regimens for this condition are unknown. [...]
2021 - 10.2340/00015555-3726
Acta dermato-venereologica, Vol. 101 Núm. 2 (2021) , p. adv00403
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5 p, 524.3 KB |
Quality of life in hidradenitis suppurativa : Validation of the hsqol-24
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Marron, S.E. (Spanish Research Group of Dermatology and Psychiatry (GEDEPSI) of the Spanish Academy of Dermatology and Venereology (AEDV)) ;
Gomez-Barrera, M. (University of San Jorge. Pharmacoeconomics & Outcomes Research Iberia) ;
Tomas-Aragones, L. (Department of Psychology. University of Zaragoza) ;
Goni-Navarro, A. (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Vilarrasa-Rull, Eva (Institut d'Investigació Biomèdica Sant Pau) ;
Díaz Díaz, R.M (Dermatology Department. University Hospital Infanta Sofía. San Sebastián de los Reyes. Madrid. 9 Dermatology Department. Royo Villanova Hospital) ;
Garcia-Latasa De Aranibar, F.J. (Aragon Psychodermatology Research Group (GAI+PD)) ;
Campos, Ricardo (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Fuentelsaz-Del-barrio, V. (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Gilaberte-Calzada, Y. (Hospital Universitario Miguel Servet (Saragossa)) ;
Gracia-Cazaña, T. (Dermatology Department. Barbastro Hospital) ;
Morales-Callaghan, A.M. (Aragon Psychodermatology Research Group (GAI+PD)) ;
Ros Abarca, Sandra (Institut d'Investigació Biomèdica Sant Pau) ;
Madrid-Alvarez, M.B. (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
To date, there are no disease-specific instruments in Spanish to assess quality of life of patients with hidra-denitis suppurativa. A multicentre study was pre-viously carried out in Spain between 2016 and 2017 to develop the Hidradenitis Suppurativa Quality of Life-24 (HSQoL-24), a disease-specific questionnaire to assess quality of life in patients with hidradenitis suppurativa. [...]
2021 - 10.2340/00015555-3905
Acta dermato-venereologica, Vol. 101 Núm. 8 (august 2021) , p. adv00529
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